145 citations · 550 across the 21 of their papers we have counts for
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A multiscale radiation biophysical stochastic model describing the cell survival response at ultra-high dose rate
Marco Battestini, Marta Missiaggia, Sara Bolzoni +2
Ultra-high dose-rate (UHDR) radiotherapy, characterized by an extremely high radiation delivery rate, represents one of the most recent and promising frontier in radiotherapy. UHDR…
May oxygen depletion explain the FLASH effect? A chemical track structure analysis
Daria Boscolo, Emanuele Scifoni, Marco Durante +2
Background and purpose: Recent observations in animal models show that ultra-high dose rate ("FLASH") radiation treatment significantly reduces normal tissue toxicity maintaining a…
The Generalized Stochastic Microdosimetric Model: the main formulation
F. Cordoni, M. Missiaggia, A. Attili +3
The present work introduces a rigorous stochastic model, named Generalized Stochastic Microdosimetric Model (GSM2), to describe biological damage induced by ionizing radiation. Sta…
Spectra of secondary electrons generated in water by energetic ions
Emanuele Scifoni, Eugene Surdutovich, Andrey V. Solov'yov
The energy distributions of secondary electrons produced by energetic carbon ions (in the energy range used, e.g., in hadron therapy), incident on liquid water, are discussed. For…
Physics of ion beam cancer therapy: a multi-scale approach
Andrey V. Solov'yov, Eugene Surdutovich, Emanuele Scifoni +2
We propose a multi-scale approach to understand the physics related to ion-beam cancer therapy. It allows the calculation of the probability of DNA damage as a result of irradiatio…
Ion-beam therapy: from electron production in tissue like media to DNA damage estimations
Emanuele Scifoni, Eugene Surdutovich, Andrey Solov'yov +3
Radiation damage induced by ion beams is traditionally treated at different levels of theoretical approaches, for the different scales and mechanisms involved.We present here detai…