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20232025
most citedBayesian electron density determination from sparse and noisy single-molecule X-ray scattering images

3 citations · 7 across the 5 of their papers we have counts for

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5 papers

physics.comp-ph2025★ 1 cited

Bayesian MINFLUX localization microscopy

Steffen Schultze, Helmut Grubmüller

MINFLUX microscopy allows for localization of fluorophores with nanometer precision using targeted scanning with an illumination profile with a minimum. However, current scanning p…

physics.comp-ph2025

Structure determination from single-molecule X-ray scattering images using stochastic gradient ascent

Steffen Schultze, D. Russell Luke, Helmut Grubmüller

Scattering experiments using ultrashort X-ray free electron laser (XFEL) pulses have opened a new path for structure determination of a wide variety of specimens, including nano-cr…

physics.comp-ph2024★ 3 cited

Bayesian electron density determination from sparse and noisy single-molecule X-ray scattering images

Steffen Schultze, Helmut Grubmüller

Single molecule X-ray scattering experiments using free electron lasers hold the potential to resolve both single structures and structural ensembles of biomolecules. However, mole…

math.OC2024★ 1 cited

Stochastic Algorithms for Large-Scale Composite Optimization: the Case of Single-Shot X-FEL Imaging

D. Russell Luke, Steffen Schultze, Helmut Grubmüller

We apply a recently developed framework for analyzing the convergence of stochastic algorithms to the general problem of large-scale nonconvex composite optimization more generally…

physics.comp-ph2023★ 2 cited

De novo structural ensemble determination from single-molecule X-ray scattering: A Bayesian approach

Steffen Schultze, Helmut Grubmüller

Single molecule X-ray scattering experiments with free electron lasers have opened a new route to the structure determination of biomolecules. Because typically only very few photo…