4 papers · 1 filter
Implementing the principal stratum strategy for intercurrent events with survival outcomes: a tutorial
Xiaoxiao Zhou, Joyce Chen, Pallavi Mishra-Kalyani +5
The International Council for Harmonization (ICH) E9 (R1) addendum provides the estimand framework to formulate treatment effects in a clinical trial. One of the attributes of an e…
Two-stage Least Squares with Clustered Data under the Local Average Treatment Effect Framework
Anqi Zhao, Peng Ding, Fan Li
To estimate the causal effect of an endogenous treatment using clustered data, the canonical two-stage least squares (2sls) estimates a linear regression of the outcome on treatmen…
Two-stage least squares with treatment-covariate interactions for treatment effect heterogeneity
Anqi Zhao, Peng Ding, Fan Li
Treatment effect heterogeneity with respect to covariates is common in instrumental variable (IV) analyses. An intuitive approach, which we call the interacted two-stage least squa…
Covariate adjustment in randomized experiments with missing outcomes and covariates
Anqi Zhao, Peng Ding, Fan Li
Covariate adjustment can improve precision in analyzing randomized experiments. With fully observed data, regression adjustment and propensity score weighting are asymptotically eq…