20 citations · 30 across the 4 of their papers we have counts for
4 papers
Out-of-equilibrium selection pressure enhances inference from protein sequence data
Nicola Dietler, Cyril Malbranke, Anne-Florence Bitbol
Homologous proteins have similar three-dimensional structures and biological functions that shape their sequences. The resulting coevolution-driven correlations underlie methods fr…
Impact of phylogeny on the inference of functional sectors from protein sequence data
Nicola Dietler, Alia Abbara, Subham Choudhury +1
Statistical analysis of multiple sequence alignments of homologous proteins has revealed groups of coevolving amino acids called sectors. These groups of amino-acid sites feature c…
Impact of phylogeny on structural contact inference from protein sequence data
Nicola Dietler, Umberto Lupo, Anne-Florence Bitbol
Local and global inference methods have been developed to infer structural contacts from multiple sequence alignments of homologous proteins. They rely on correlations in amino-aci…
Correlations from structure and phylogeny combine constructively in the inference of protein partners from sequences
Andonis Gerardos, Nicola Dietler, Anne-Florence Bitbol
Inferring protein-protein interactions from sequences is an important task in computational biology. Recent methods based on Direct Coupling Analysis (DCA) or Mutual Information (M…