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q-bio.MN2012
Assessing the significance of knockout cascades in metabolic networks
Oriol Güell, Francesc Sagués, Georg Basler +2
Complex networks have been shown to be robust against random structural perturbations, but vulnerable against targeted attacks. Robustness analysis usually simulates the removal of…
q-bio.MN2012
Predicting effects of structural stress in a genome-reduced model bacterial metabolism
Oriol Güell, Francesc Sagués, M. Ángeles Serrano
We studied in silico effects of structural stress in Mycoplasma pneumoniae, a genome-reduced model bacterial organism, by tracking the damage propagating on its metabolic network a…