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q-bio.CB2026
Parameter Identifiability Under Limited Experimental Data in Age-Structured Models of the Cell Cycle
Ruby E. Nixson, Helen M. Byrne, Joe M. Pitt-Francis +1
The mitotic cell cycle governs DNA replication and cell division. The effectiveness of radiotherapy and chemotherapy depends on cell-cycle position, with increased resistance durin…
q-bio.CB2023
Using a probabilistic approach to derive a two-phase model of flow-induced cell migration
Yaron Ben-Ami, Joe M. Pitt-Francis, Philip K. Maini +1
Interstitial fluid flow is a feature of many solid tumours. In vitro Experiments have shown that such fluid flow can direct tumour cell movement upstream or downstream depending on…