3 papers
q-bio.CB2026
Parameter Identifiability Under Limited Experimental Data in Age-Structured Models of the Cell Cycle
Ruby E. Nixson, Helen M. Byrne, Joe M. Pitt-Francis +1
The mitotic cell cycle governs DNA replication and cell division. The effectiveness of radiotherapy and chemotherapy depends on cell-cycle position, with increased resistance durin…
q-bio.CB2023
Using a probabilistic approach to derive a two-phase model of flow-induced cell migration
Yaron Ben-Ami, Joe M. Pitt-Francis, Philip K. Maini +1
Interstitial fluid flow is a feature of many solid tumours. In vitro Experiments have shown that such fluid flow can direct tumour cell movement upstream or downstream depending on…
q-bio.QM2022
Structural features of microvascular networks trigger blood-flow oscillations
Yaron Ben-Ami, George W. Atkinson, Joe M. Pitt-Francis +2
We analyse mathematical models in order to understand how microstructural features of vascular networks may affect blood-flow dynamics, and to identify particular characteristics t…