33 citations · 71 across the 4 of their papers we have counts for
4 papers
Simulations of tubulin sheet polymers as possible structural intermediates in microtubule assembly
Zhanghan Wu, Hong-Wei Wang, Weihua Mu +3
The microtubule assembly process has been extensively studied, but the underlying molecular mechanism remains poorly understood. The structure of an artificially generated sheet po…
Amplification and detection of single molecule conformational fluctuation through a protein interaction network with bimodal distributions
Zhanghan Wu, Vlad Elgart, Hong Qian +1
A protein undergoes conformational dynamics with multiple time scales, which results in fluctuating enzyme activities. Recent studies in single molecule enzymology have observe thi…
Mori-Zwanzig projection formalism: from linear to nonlinear
Jianhua Xing
The Mori-Zwanzig projection formalism is widely used in studying systems with many degrees of freedom. We used a system-bath Hamiltonian system to show that the Mori's and Zwanzig'…
A non-equilibrium dynamic mechanism for the allosteric effect
Jianhua Xing
Allosteric regulation is often viewed as thermodynamic in nature. However protein internal motions during an enzymatic reaction cycle can be slow hopping processes over numerous po…