32 citations · 81 across the 6 of their papers we have counts for
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q-bio.SC2011★ 32 cited
Transcription factor search for a DNA promoter in a three-states model
Juergen Reingruber, David Holcman
To ensure fast gene activation, Transcription Factors (TF) use a mechanism known as facilitated diffusion to find their DNA promoter site. Here we analyze such a process where a TF…
q-bio.NC2011
The Narrow Escape problem in a flat cylindrical microdomain with application to diffusion in the synaptic cleft
Juergen Reingruber, David Holcman
The mean first passage time (MFPT) for a Brownian particle to reach a small target in cellular microdomains is a key parameter for chemical activation. Although asymptotic estimati…