1 citations · 1 across the 1 of their papers we have counts for
2 papers
stat.ME2026
PK/PD-integrated Bayesian platform design for phase II dose regimen optimization
Axel Vuorinen, Antoine Guillon, Emmanuelle Comets +2
Early-phase dose-finding methods increasingly assess toxicity and efficacy jointly, but comparisons based only on administered dose may inadequately characterize regimens differing…
stat.AP2024★ 1 cited
Straightforward Phase I Dose-Finding Design for Healthy Volunteers Accounting for Surrogate Activity Biomarkers
Sandrine Boulet, Emmanuelle Comets, Antoine Guillon +5
Conventionally, a first-in-human phase I trial in healthy volunteers aims to confirm the safety of a drug in humans. In such situations, volunteers should not suffer from any safet…