2 papers
cs.LG2026
Towards A Generative Protein Evolution Machine with DPLM-Evo
Xinyou Wang, Liang Hong, Jiasheng Ye +4
Proteins are shaped by gradual evolution under biophysical and functional constraints. Protein language models learn rich evolutionary constraints from large-scale sequences, and d…
q-bio.BM2024
RiboDiffusion: Tertiary Structure-based RNA Inverse Folding with Generative Diffusion Models
Han Huang, Ziqian Lin, Dongchen He +2
RNA design shows growing applications in synthetic biology and therapeutics, driven by the crucial role of RNA in various biological processes. A fundamental challenge is to find f…