2 papers
q-bio.QM2025
Accurate RNA 3D structure prediction using a language model-based deep learning approach
Tao Shen, Zhihang Hu, Siqi Sun +14
Accurate prediction of RNA three-dimensional (3D) structure remains an unsolved challenge. Determining RNA 3D structures is crucial for understanding their functions and informing…
q-bio.QM2024
TemPL: A Novel Deep Learning Model for Zero-Shot Prediction of Protein Stability and Activity Based on Temperature-Guided Language Modeling
Pan Tan, Mingchen Li, Liang Zhang +2
We introduce TemPL, a novel deep learning approach for zero-shot prediction of protein stability and activity, harnessing temperature-guided language modeling. By assembling an ext…