2 citations · 3 across the 6 of their papers we have counts for
5 papers · 1 filter
Correcting for Missing Data When Evaluating Surrogate Markers in a Clinical Trial
Sarah C. Lotspeich, P. D. Anh. Nguyen, Layla Parast
Evaluating treatment effects is critical in clinical trials but sometimes involves lengthy, invasive, or costly follow-up procedures. In these cases, surrogate markers, which provi…
Symmetric Vaccine Efficacy
Lucy D'Agostino McGowan, Sarah C. Lotspeich, Michael G. Hudgens
Traditional measures of vaccine efficacy (VE) are inherently asymmetric, constrained above by but unbounded below. As a result, VE estimates and corresponding confidence interv…
Two-phase validation sampling via principal components to improve efficiency in multi-model estimation from error-prone biomedical databases
Sarah C. Lotspeich, Cole Manschot
Two-phase sampling offers a cost-effective way to validate error-prone covariate measurements in biomedical databases. Inexpensive or easy-to-obtain information is collected for th…
Linking Potentially Misclassified Healthy Food Access to Diabetes Prevalence
Ashley E. Mullan, P. D. Anh Nguyen, Sarah C. Lotspeich
Access to healthy food is key to maintaining a healthy lifestyle and can be quantified by the distance to the nearest grocery store. However, calculating this distance forces a tra…
Overcoming data challenges through enriched validation and targeted sampling to measure whole-person health in electronic health records
Sarah C. Lotspeich, Sheetal Kedar, Rabeya Tahir +7
The allostatic load index (ALI) is a 10-component measure of whole-person health. Data from electronic health records (EHR) present a huge opportunity to operationalize the ALI in…