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20242026
most citedOvercoming data challenges through enriched validation and targeted sampling to measure whole-person health in electronic health records

2 citations · 3 across the 6 of their papers we have counts for

collaborators

8 papers

stat.AP2026

Prediction Modeling from an EHR-Derived Allostatic Load Index with Informatively Missing Biomarkers: A Case Study

Grayson E. Weavil, Joseph Rigdon, Sarah C. Lotspeich

Embedding a standardized measure of physiologic stress in electronic health records (EHR) could be instrumental to preventative care. The allostatic load index (ALI), calculated fr…

stat.ME2026

Correcting for Missing Data When Evaluating Surrogate Markers in a Clinical Trial

Sarah C. Lotspeich, P. D. Anh. Nguyen, Layla Parast

Evaluating treatment effects is critical in clinical trials but sometimes involves lengthy, invasive, or costly follow-up procedures. In these cases, surrogate markers, which provi…

stat.ME2025

Symmetric Vaccine Efficacy

Lucy D'Agostino McGowan, Sarah C. Lotspeich, Michael G. Hudgens

Traditional measures of vaccine efficacy (VE) are inherently asymmetric, constrained above by but unbounded below. As a result, VE estimates and corresponding confidence interv…

stat.ME2025

Two-phase validation sampling via principal components to improve efficiency in multi-model estimation from error-prone biomedical databases

Sarah C. Lotspeich, Cole Manschot

Two-phase sampling offers a cost-effective way to validate error-prone covariate measurements in biomedical databases. Inexpensive or easy-to-obtain information is collected for th…

cs.LG2025

On Using Large Language Models to Enhance Clinically-Driven Missing Data Recovery Algorithms in Electronic Health Records

Sarah C. Lotspeich, Abbey Collins, Brian J. Wells +3

Objective: Electronic health records (EHR) data are prone to missingness and errors. Previously, we devised an "enriched" chart review protocol where a "roadmap" of auxiliary diagn…

stat.ME2025

Linking Potentially Misclassified Healthy Food Access to Diabetes Prevalence

Ashley E. Mullan, P. D. Anh Nguyen, Sarah C. Lotspeich

Access to healthy food is key to maintaining a healthy lifestyle and can be quantified by the distance to the nearest grocery store. However, calculating this distance forces a tra…

stat.ME2025★ 2 cited

Overcoming data challenges through enriched validation and targeted sampling to measure whole-person health in electronic health records

Sarah C. Lotspeich, Sheetal Kedar, Rabeya Tahir +7

The allostatic load index (ALI) is a 10-component measure of whole-person health. Data from electronic health records (EHR) present a huge opportunity to operationalize the ALI in…

stat.AP2024★ 1 cited

Combining straight-line and map-based distances to investigate the connection between proximity to healthy foods and disease

Sarah C. Lotspeich, Ashley E. Mullan, Lucy D'Agostino McGowan +1

Healthy foods are essential for a healthy life, but accessing healthy food can be more challenging for some people than others. This disparity in food access may lead to disparitie…