239 citations · 996 across the 29 of their papers we have counts for
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Transcriptional bursting in gene expression: analytical results for general stochastic models
Niraj Kumar, Abhyudai Singh, Rahul V. Kulkarni
Gene expression in individual cells is highly variable and sporadic, often resulting in the synthesis of mRNAs and proteins in bursts. Bursting in gene expression is known to impac…
Exact distributions for stochastic gene expression models with bursting and feedback
Niraj Kumar, Thierry Platini, Rahul V. Kulkarni
Stochasticity in gene expression can give rise to fluctuations in protein levels and lead to phenotypic variation across a population of genetically identical cells. Recent experim…
Moment Closure Approximations in a Genetic Negative Feedback Circuit
Mohammad Soltani, Cesar Vargas, Niraj Kumar +2
Auto-regulation, a process wherein a protein negatively regulates its own production, is a common motif in gene expression networks. Negative feedback in gene expression plays a cr…