6 citations · 15 across the 8 of their papers we have counts for
9 papers
LabAgent: Customize Any Research Hubs for Scientific Discoveries Using AI Agents
Lei Liu, Yikun Zhang, Jialin Chen +7
Scientific research is a continuous process that emphasizes inheritance. Methods developed by predecessors are often expanded upon by new researchers to explore more novel and in-d…
Predicting Immune Biomarkers with MultiModal Mixture-of-Expert Pathology Foundation Models Empowers Precision Oncology
Tianyu Liu, Ziqing Wang, Zhaokang Liang +12
Predicting immune biomarkers associated with the tumor immune microenvironment (TIME) is critical for advancing precision oncology, yet existing approaches are largely limited to s…
Benchmarking AI Agents for Addressing Scientific Challenges Across Scales
Tianyu Liu, Allen Xin Wang, Antonia Panescu +30
AI agents are increasingly being developed to accelerate scientific discovery, yet their practical capabilities in real research settings remain poorly understood. Existing benchma…
Accelerating Scientific Discovery with Autonomous Goal-evolving Agents
Yuanqi Du, Botao Yu, Tianyu Liu +25
There has been unprecedented interest in developing agents that expand the boundary of scientific discovery, primarily by optimizing quantitative objective functions specified by s…
Scalable Generation of Spatial Transcriptomics from Histology Images via Whole-Slide Flow Matching
Tinglin Huang, Tianyu Liu, Mehrtash Babadi +2
Spatial transcriptomics (ST) has emerged as a powerful technology for bridging histology imaging with gene expression profiling. However, its application has been limited by low th…
Reaction-conditioned De Novo Enzyme Design with GENzyme
Chenqing Hua, Jiarui Lu, Yong Liu +7
The introduction of models like RFDiffusionAA, AlphaFold3, AlphaProteo, and Chai1 has revolutionized protein structure modeling and interaction prediction, primarily from a binding…
SurfPro: Functional Protein Design Based on Continuous Surface
Zhenqiao Song, Tinglin Huang, Lei Li +1
How can we design proteins with desired functions? We are motivated by a chemical intuition that both geometric structure and biochemical properties are critical to a protein's fun…
Protein-Nucleic Acid Complex Modeling with Frame Averaging Transformer
Tinglin Huang, Zhenqiao Song, Rex Ying +1
Nucleic acid-based drugs like aptamers have recently demonstrated great therapeutic potential. However, experimental platforms for aptamer screening are costly, and the scarcity of…
Generative Enzyme Design Guided by Functionally Important Sites and Small-Molecule Substrates
Zhenqiao Song, Yunlong Zhao, Wenxian Shi +3
Enzymes are genetically encoded biocatalysts capable of accelerating chemical reactions. How can we automatically design functional enzymes? In this paper, we propose EnzyGen, an a…