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stat.ME2025
Integrating tumor burden with survival outcome for treatment effect evaluation in oncology trials
Saurabh Bhandari, Michael J. Daniels, Chenguang Wang
In early-phase cancer clinical trials, the limited availability of data presents significant challenges in developing a framework to efficiently quantify treatment effectiveness. T…
stat.ME2025
Assessing treatment efficacy for interval-censored endpoints using multistate semi-Markov models fit to multiple data streams
Raphael Morsomme, C. Jason Liang, Allyson Mateja +4
We introduce a computationally efficient and general approach for utilizing multiple, possibly interval-censored, data streams to study complex biomedical endpoints using multistat…