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stat.ME2025
A Clustering Approach for Basket Trials Based on Treatment Response Trajectories
Masahiro Kojima, Keisuke Hanada, Atsuya Sato
Heterogeneity in efficacy is sometimes observed across baskets in basket trials. In this study, we propose a model-free clustering framework that groups baskets based on transition…
stat.ME2025
Sample size re-estimation in blinded hybrid-control design using inverse probability weighting
Masahiro Kojima, Shunichiro Orihara, Keisuke Hanada +1
With the increasing availability of data from historical studies and real-world data sources, hybrid control designs that incorporate external data into the evaluation of current s…