activity
20232026
most citedVirtual histological staining of unlabeled autopsy tissue

63 citations · 200 across the 14 of their papers we have counts for

collaborators

14 papers

physics.app-ph2026

Continuous quantification of viral plaque dynamics using ultra-large-area label-free imaging enables rapid antiviral susceptibility testing

Merve Eryilmaz, Yuzhu Li, Xiao Wang +8

The plaque reduction assay (PRA) remains the gold standard for antiviral susceptibility testing, evaluating drug potency by measuring reductions in plaque-forming units (PFUs). How…

physics.optics2026

Compressive single-pixel imaging via a wavelength-multiplexed spatially incoherent diffractive optical processor

Xiao Wang, Yiyang Wu, Yuntian Wang +8

Despite offering high sensitivity, a high signal-to-noise ratio, and a broad spectral range, single-pixel imaging (SPI) is limited by low measurement efficiency and long data-acqui…

physics.med-ph2026

Automated HER2 scoring with uncertainty quantification using lensfree holography and deep learning

Che-Yung Shen, Xilin Yang, Yuzhu Li +2

Accurate assessment of human epidermal growth factor receptor 2 (HER2) expression is critical for breast cancer diagnosis, prognosis, and therapy selection; yet, most existing digi…

physics.med-ph2025★ 4 cited

Deep learning-enhanced dual-mode multiplexed optical sensor for point-of-care diagnostics of cardiovascular diseases

Gyeo-Re Han, Merve Eryilmaz, Artem Goncharov +12

Rapid and accessible cardiac biomarker testing is essential for the timely diagnosis and risk assessment of myocardial infarction (MI) and heart failure (HF), two interrelated cond…

physics.optics2025

Detection and imaging of chemicals and hidden explosives using terahertz time-domain spectroscopy and deep learning

Xinghe Jiang, Yuhang Li, Yuzhu Li +3

Detecting concealed chemicals and explosives remains a critical challenge in global security. Terahertz time-domain spectroscopy (THz-TDS) offers a promising non-invasive and stand…

physics.med-ph2025★ 3 cited

Deep learning-enabled virtual multiplexed immunostaining of label-free tissue for vascular invasion assessment

Yijie Zhang, Cagatay Isil, Xilin Yang +6

Immunohistochemistry (IHC) has transformed clinical pathology by enabling the visualization of specific proteins within tissue sections. However, traditional IHC requires one tissu…

cs.CV2024★ 3 cited

Deep Learning-based Detection of Bacterial Swarm Motion Using a Single Image

Yuzhu Li, Hao Li, Weijie Chen +6

Distinguishing between swarming and swimming, the two principal forms of bacterial movement, holds significant conceptual and clinical relevance. This is because bacteria that exhi…

eess.IV2024★ 27 cited

Pixel super-resolved virtual staining of label-free tissue using diffusion models

Yijie Zhang, Luzhe Huang, Nir Pillar +3

Virtual staining of tissue offers a powerful tool for transforming label-free microscopy images of unstained tissue into equivalents of histochemically stained samples. This study…

physics.med-ph2024★ 2 cited

Label-free evaluation of lung and heart transplant biopsies using tissue autofluorescence-based virtual staining

Yuzhu Li, Nir Pillar, Tairan Liu +12

Organ transplantation serves as the primary therapeutic strategy for end-stage organ failures. However, allograft rejection is a common complication of organ transplantation. Histo…

eess.IV2024★ 18 cited

A robust and scalable framework for hallucination detection in virtual tissue staining and digital pathology

Luzhe Huang, Yuzhu Li, Nir Pillar +3

Histopathological staining of human tissue is essential for disease diagnosis. Recent advances in virtual tissue staining technologies using artificial intelligence (AI) alleviate…

eess.IV2024★ 35 cited

Automated HER2 Scoring in Breast Cancer Images Using Deep Learning and Pyramid Sampling

Sahan Yoruc Selcuk, Xilin Yang, Bijie Bai +12

Human epidermal growth factor receptor 2 (HER2) is a critical protein in cancer cell growth that signifies the aggressiveness of breast cancer (BC) and helps predict its prognosis.…

physics.med-ph2024★ 26 cited

Virtual birefringence imaging and histological staining of amyloid deposits in label-free tissue using autofluorescence microscopy and deep learning

Xilin Yang, Bijie Bai, Yijie Zhang +8

Systemic amyloidosis is a group of diseases characterized by the deposition of misfolded proteins in various organs and tissues, leading to progressive organ dysfunction and failur…

physics.optics2024★ 19 cited

Multiplexed all-optical permutation operations using a reconfigurable diffractive optical network

Guangdong Ma, Xilin Yang, Bijie Bai +8

Large-scale and high-dimensional permutation operations are important for various applications in e.g., telecommunications and encryption. Here, we demonstrate the use of all-optic…

physics.med-ph2023★ 63 cited

Virtual histological staining of unlabeled autopsy tissue

Yuzhu Li, Nir Pillar, Jingxi Li +12

Histological examination is a crucial step in an autopsy; however, the traditional histochemical staining of post-mortem samples faces multiple challenges, including the inferior s…