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cs.AI2026
Predictor-Guided Latent Space Codon Optimization for Maximizing Protein Expression
Alberto Caron, Tianyu Cui, Dmytro S. Lituiev +13
Codon optimization, the process of selecting synonymous codons to improve mRNA translation efficiency and protein expression, is central to therapeutic protein production and mRNA…
cs.CV2026
PaSTel: Anchoring Histology in Spatial Transcriptomics via Multi-Scale Hierarchical Bio-Prior Contrastive Pretraining
Azim Dehghani Amirabad, Junchao Zhu, Pushpak Pati +3
Spatial transcriptomics (ST) links tissue morphology with molecular programs, motivating multimodal pretraining methods that align histology images with gene expression. However, e…