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physics.med-ph2026
Causal machine learning reveals age-dependent radiation dose effects on mandibular osteoradionecrosis
Jingyuan Chen, Yunze Yang, Olivia M. Muller +8
Distinguishing causal relationships from statistical correlations remains a fundamental challenge in clinical research, limiting the translation of observational findings into inte…
physics.med-ph2025
Causal Machine Learning Analysis of Empirical Relative Biological Effectiveness (RBE) for Mandible Osteoradionecrosis in Head and Neck Cancer Radiotherapy
Jingyuan Chen, Zhong Liu, Yunze Yang +8
Mandible Osteoradionecrosis (ORN) is one of the most severe adverse events (AEs) for head and neck (H&N) cancer radiotherapy. Previous retrospective investigations on real-world da…