81 citations · 151 across the 3 of their papers we have counts for
3 papers
Spectral solutions to stochastic models of gene expression with bursts and regulation
Andrew Mugler, Aleksandra M. Walczak, Chris H. Wiggins
Signal-processing molecules inside cells are often present at low copy number, which necessitates probabilistic models to account for intrinsic noise. Probability distributions hav…
A stochastic spectral analysis of transcriptional regulatory cascades
Aleksandra M. Walczak, Andrew Mugler, Chris H. Wiggins
The past decade has seen great advances in our understanding of the role of noise in gene regulation and the physical limits to signaling in biological networks. Here we introduce…
Quantifying evolvability in small biological networks
Andrew Mugler, Etay Ziv, Ilya Nemenman +1
We introduce a quantitative measure of the capacity of a small biological network to evolve. We apply our measure to a stochastic description of the experimental setup of Guet et a…