3 papers
q-bio.MN2026
Restoring information in aged gene regulatory networks by single knock-ins
Ryan LeFebre, Fabrisia Ambrosio, Andrew Mugler
A hallmark of aging is loss of information in gene regulatory networks. These networks are tightly connected, raising the question of whether information could be restored by pertu…
physics.bio-ph2025
General mechanism for concentration-based cell size control
Motasem ElGamel, Lucas Ribaudo, Andrew Mugler
Cells control their size to cope with noise during growth and division. Eukaryotic cells exhibiting "sizer" control (targeting a specific size before dividing) may rely on molecula…
physics.bio-ph2023
Role of signal degradation in directional chemosensing
Ryan LeFebre, Joseph A. Landsittel, David E. Stone +1
Directional chemosensing is ubiquitous in cell biology, but some cells such as mating yeast paradoxically degrade the signal they aim to detect. While the data processing inequalit…