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math.OC2025★ 4 cited
Adaptive Nonlinear Model Predictive Control of Monoclonal Antibody Glycosylation in CHO Cell Culture
Yingjie Ma, Jing Guo, Alexis B. Dubs +2
N-glycosylation is a critical quality attribute of monoclonal antibodies (mAbs), the dominant class of biopharmaceuticals. Controlling glycosylation remains difficult due to intrin…
math.OC2024
Time-certified Input-constrained NMPC via Koopman Operator
Liang Wu, Krystian Ganko, Richard D. Braatz
Determining solving-time certificates of nonlinear model predictive control (NMPC) implementations is a pressing requirement when deploying NMPC in production environments. Such a…