1 citations · 2 across the 4 of their papers we have counts for
4 papers
A web-based user interface for Fam3PRO, a multi-gene, multi-cancer risk prediction model for families with cancer history
Xueying Chen, Jianfeng Ke, Lauren Flynn +2
Purpose: Hereditary cancer risk is key to guiding screening and prevention strategies. Cancer risks can vary by individual due to the presence or absence of high- and moderate-risk…
BreakLoops: A New Feature for the Multi-Gene, Multi-Cancer Family History-Based Model, Fam3Pro
Nicolas Kubista, Ryan Hernandez-Cancela, Jianfeng Ke +4
Previously, we presented PanelPRO, now known as Fam3PRO, an open-source R package for multi-gene, multi-cancer risk modeling with pedigree data. The initial release could not handl…
The penetrance R package for Estimation of Age Specific Risk in Family-based Studies
Nicolas Kubista, Danielle Braun, Giovanni Parmigiani
Reliable tools and software for penetrance (age-specific risk among those who carry a genetic variant) estimation are critical to improving clinical decision making and risk assess…
Adjusting for Ascertainment Bias in Meta-Analysis of Penetrance for Cancer Risk
Thanthirige Lakshika M. Ruberu, Danielle Braun, Giovanni Parmigiani +1
Multi-gene panel testing allows efficient detection of pathogenic variants in cancer susceptibility genes including moderate-risk genes such as ATM and PALB2. A growing number of s…