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20242026
most citedUnifying Sequences, Structures, and Descriptions for Any-to-Any Protein Generation with the Large Multimodal Model HelixProtX

4 citations · 9 across the 11 of their papers we have counts for

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Showing 2025Show all

6 papers · 1 filter

q-bio.GN2025

MergeDNA: Context-aware Genome Modeling with Dynamic Tokenization through Token Merging

Siyuan Li, Kai Yu, Anna Wang +7

Modeling genomic sequences faces two unsolved challenges: the information density varies widely across different regions, while there is no clearly defined minimum vocabulary unit.…

cs.LG2025

PRESCRIBE: Predicting Single-Cell Responses with Bayesian Estimation

Jiabei Cheng, Changxi Chi, Jingbo Zhou +2

In single-cell perturbation prediction, a central task is to forecast the effects of perturbing a gene unseen in the training data. The efficacy of such predictions depends on two…

cs.LG2025

HDTree: Generative Modeling of Cellular Hierarchies for Robust Lineage Inference

Zelin Zang, WenZhe Li, Yongjie Xu +5

In single-cell research, tracing and analyzing high-throughput single-cell differentiation trajectories is crucial for understanding biological processes. Key to this is the robust…

cs.LG2025

Doloris: Dual Conditional Diffusion Implicit Bridges with Sparsity Masking Strategy for Unpaired Single-Cell Perturbation Estimation

Changxi Chi, Jun Xia, Yufei Huang +9

Estimating single-cell responses across various perturbations facilitates the identification of key genes and enhances drug screening, significantly boosting experimental efficienc…

q-bio.QM2025

GRAPE: Heterogeneous Graph Representation Learning for Genetic Perturbation with Coding and Non-Coding Biotype

Changxi Chi, Jun Xia, Jingbo Zhou +3

Predicting genetic perturbations enables the identification of potentially crucial genes prior to wet-lab experiments, significantly improving overall experimental efficiency. Sinc…

cs.LG2025

NodeReg: Mitigating the Imbalance and Distribution Shift Effects in Semi-Supervised Node Classification via Norm Consistency

Shenzhi Yang, Jun Xia, Jingbo Zhou +2

Aggregating information from neighboring nodes benefits graph neural networks (GNNs) in semi-supervised node classification tasks. Nevertheless, this mechanism also renders nodes s…