8 citations · 15 across the 11 of their papers we have counts for
10 papers
When LLM Meets Tree Search: A Systematic View of Inference as Search in Large Language Models
Jiaqi Wei, Xiang Zhang, Yuejin Yang +10
As pretraining scaling laws approach saturation, Test-Time Scaling (TTS) has emerged as an important direction for improving reasoning by allocating inference-time compute to a fix…
ResearchClawBench: A Benchmark for End-to-End Autonomous Scientific Research
Wanghan Xu, Shuo Li, Tianlin Ye +48
AI coding agents are increasingly used for scientific work, but their end-to-end autonomous research capability remains difficult to verify. We present ResearchClawBench, a benchma…
Accurate de novo sequencing of the modified proteome with OmniNovo
Yuhan Chen, Shang Qu, Zhiqiang Gao +13
Post-translational modifications (PTMs) serve as a dynamic chemical language regulating protein function, yet current proteomic methods remain blind to a vast portion of the modifi…
Unifying Tree Search Algorithm and Reward Design for LLM Reasoning: A Survey
Jiaqi Wei, Xiang Zhang, Yuejin Yang +10
Deliberative tree search is a cornerstone of modern Large Language Model (LLM) research, driving the pivot from brute-force scaling toward algorithmic efficiency. This single parad…
Bidirectional Representations Augmented Autoregressive Biological Sequence Generation
Xiang Zhang, Jiaqi Wei, Zijie Qiu +5
Autoregressive (AR) models, common in sequence generation, are limited in many biological tasks such as de novo peptide sequencing and protein modeling by their unidirectional natu…
Curriculum Learning for Biological Sequence Prediction: The Case of De Novo Peptide Sequencing
Xiang Zhang, Jiaqi Wei, Zijie Qiu +4
Peptide sequencing-the process of identifying amino acid sequences from mass spectrometry data-is a fundamental task in proteomics. Non-Autoregressive Transformers (NATs) have prov…
Universal Biological Sequence Reranking for Improved De Novo Peptide Sequencing
Zijie Qiu, Jiaqi Wei, Xiang Zhang +6
De novo peptide sequencing is a critical task in proteomics. However, the performance of current deep learning-based methods is limited by the inherent complexity of mass spectrome…
On the Performance Analysis of Momentum Method: A Frequency Domain Perspective
Xianliang Li, Jun Luo, Zhiwei Zheng +5
Momentum-based optimizers are widely adopted for training neural networks. However, the optimal selection of momentum coefficients remains elusive. This uncertainty impedes a clear…
BEACON: Benchmark for Comprehensive RNA Tasks and Language Models
Yuchen Ren, Zhiyuan Chen, Lifeng Qiao +10
RNA plays a pivotal role in translating genetic instructions into functional outcomes, underscoring its importance in biological processes and disease mechanisms. Despite the emerg…
ContraNovo: A Contrastive Learning Approach to Enhance De Novo Peptide Sequencing
Zhi Jin, Sheng Xu, Xiang Zhang +6
De novo peptide sequencing from mass spectrometry (MS) data is a critical task in proteomics research. Traditional de novo algorithms have encountered a bottleneck in accuracy due…