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stat.ME2026
Bayesian Sample Size Determination: Sampling Distribution Estimation or Exploration?
Luke Hagar, Paul Gustafson
To design many Bayesian studies, the sample size is chosen to attain sufficient power to reject a null hypothesis or a desired probability that an interval estimate is sufficiently…
stat.ME2026
COBRA-DOSE: Copula-based Bayesian Model Averaging for Dose Selection
Luke Hagar, Min Zhang, Ranjeny Thomas +1
Early-phase clinical trials for dose selection typically enrol few patients and aim to identify doses that are both safe and promising for further study. While traditional approach…
stat.ME2026
Computationally Efficient Experimental Design with Generalized Posteriors
Luke Hagar, James M. McGree
The hybrid approach to experimental design aims to control frequentist operating characteristics of Bayesian decision procedures. These operating characteristics are assessed by si…