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physics.bio-ph2026
Imaging biofilms in three dimensions: modalities, quantitative readouts, and the path to four-dimensional measurement
Seongsoo Lee, YongKeun Park
Biofilms are spatially structured microbial communities whose architecture, chemistry, mechanics, and cellular states evolve over time. Bulk assays and two-dimensional projections…
physics.bio-ph2026
Holotomography in 2025: From Morphometric Imaging to AI-Driven Multimodal Phenotyping
YongKeun Park
By 2025, holotomography (HT) has matured from a niche optical modality into a versatile platform for quantitative, label-free imaging in biomedicine. By reconstructing the three-di…