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stat.AP2024
A mixed effects cosinor modelling framework for circadian gene expression
Michael T. Gorczyca
The cosinor model is frequently used to represent the oscillatory behavior of different genes over time. When data are collected from multiple individuals, the cosinor model is est…
stat.ME2024
On Weighted Trigonometric Regression for Suboptimal Designs in Circadian Biology Studies
Michael Gorczyca, Justice Sefas
Studies in circadian biology often use trigonometric regression to model phenomena over time. Ideally, protocols in these studies would collect samples at evenly distributed and eq…