3 papers
stat.AP2026
A Note on Harmonic Underspecification in Log-Normal Trigonometric Regression
Michael T. Gorczyca
Analysis of biological rhythm data often involves performing least squares trigonometric regression, which models the oscillations of a response over time as a sum of sinusoidal co…
stat.AP2025
Two-Stage Trigonometric Regression for Modeling Circadian Rhythms
Michael T. Gorczyca, Jenna D. Li, Charissa M. Newkirk +2
Gene expression levels, hormone secretion, and internal body temperature each oscillate over an approximately 24-hour cycle, or display circadian rhythms. Many circadian biology st…
stat.AP2024
A mixed effects cosinor modelling framework for circadian gene expression
Michael T. Gorczyca
The cosinor model is frequently used to represent the oscillatory behavior of different genes over time. When data are collected from multiple individuals, the cosinor model is est…