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physics.bio-ph2026
A stochastic agent-based extension of the GSM model for particle therapy: cell-cycle dynamics, dose-rate dependence, and fractionation effects
Francesco G. Cordoni, Marco Battestini, Marta Missiaggia
We present a stochastic agent-based extension of the Generalized Stochastic Microdosimetric Model (GSM) that links microscopic energy deposition by ionizing radiation to popula…
physics.bio-ph2024
A multiscale radiation biophysical stochastic model describing the cell survival response at ultra-high dose rate
Marco Battestini, Marta Missiaggia, Sara Bolzoni +2
Ultra-high dose-rate (UHDR) radiotherapy, characterized by an extremely high radiation delivery rate, represents one of the most recent and promising frontier in radiotherapy. UHDR…