Showing 2026Show all
3 papers · 1 filter
stat.ME2026
Empirical Simulation of Survival and Mixed-Type Data for Clinical Trial Design
Yao Chen, Jiren Sun, Yuxin Ding +2
Simulating realistic time-to-event data is essential for planning and evaluating complex clinical trial designs. Conventional approaches often sample event times from parametric fa…
stat.ME2026
Capturing Cumulative Disease Burden in Chronic Kidney Disease Outcome Trials: Area Under the Curve and Restricted Mean Time in Favor of Treatment Beyond Conventional Time-to-First Analysis
Jiren Sun, Tuo Wang, Yu Du
Chronic kidney disease (CKD) affects millions worldwide and progresses irreversibly through stages culminating in end-stage renal disease (ESRD) and death. Outcome trials in CKD tr…
stat.ME2026
An Empirical Method for Analyzing Count Data
Jiren Sun, Linda Amoafo, Yongming Qu
Count endpoints are common in clinical trials, particularly for recurrent events such as hypoglycemia. When interest centers on comparing overall event rates between treatment grou…