3 papers
stat.ME2026
Capturing Cumulative Disease Burden in Chronic Kidney Disease Outcome Trials: Area Under the Curve and Restricted Mean Time in Favor of Treatment Beyond Conventional Time-to-First Analysis
Jiren Sun, Tuo Wang, Yu Du
Chronic kidney disease (CKD) affects millions worldwide and progresses irreversibly through stages culminating in end-stage renal disease (ESRD) and death. Outcome trials in CKD tr…
stat.ME2026
An Empirical Method for Analyzing Count Data
Jiren Sun, Linda Amoafo, Yongming Qu
Count endpoints are common in clinical trials, particularly for recurrent events such as hypoglycemia. When interest centers on comparing overall event rates between treatment grou…
stat.ME2025
On the Proportional Principal Stratum Hazards Model
Jiren Sun, Thomas D. Cook
In clinical trials involving both mortality and morbidity, an active treatment can influence the observed risk of the first non-fatal event either directly, through its effect on t…