3 papers
q-bio.PE2026
Modeling tumor cell heterogeneity and plasticity in adaptive therapy
Rui Yue, Chenghang Li, Jinzhi Lei
Adaptive therapy (AT) is designed to postpone the emergence of drug resistance by exploiting evolutionary competition among tumor subclones. Most mathematical models of AT assume a…
q-bio.CB2026
Effects of multi-phase control mechanism on fibroblast dynamics: A segmented mathematical modeling approach
Shuqi Fan, Yuhang Zhang, Jinzhi Lei
Cell size is a fundamental determinant of cellular physiology, influencing processes such as growth, division, and function. In this study, we develop a segmented mathematical fram…
q-bio.CB2025
Quantitative analysis of cell size control mechanisms
Shuqi Fan, Jinzhi Lei
Cell size control is crucial for maintaining cellular function and homeostasis. In this study, we develop a first-order partial differential equation model to examine the effects o…