activity
20062023
most citedSequential recruitment and combinatorial assembling of multiprotein complexes in transcriptional activation

32 citations · 174 across the 25 of their papers we have counts for

collaborators

25 papers

math.CA2023

Algebraic Multiplicity and the Poincaré Problem

Jinzhi Lei, Lijun Yang

In this paper we derive an upper bound for the degree of the strict invariant algebraic curve of a polynomial system in the complex project plane under generic condition. The resul…

q-bio.QM2023

Dynamics of cell-type transition mediated by epigenetic modifications

Rongsheng Huang, Qiaojun Situ, Jinzhi Lei

Maintaining tissue homeostasis requires appropriate regulation of stem cell differentiation. The Waddington landscape posits that gene circuits in a cell form a potential landscape…

math-ph2022

Power law dependence in a random differential equation

Qiuxin Lv, Wei Ma, Jinzhi Lei

This paper studies a random differential equation with random switch perturbations. We explore how the maximum displacement from the equilibrium state depends on the statistical pr…

q-bio.CB2020★ 12 cited

Using single-cell entropy to describe the dynamics of reprogramming and differentiation of induced pluripotent stem cells

Yusong Ye, Zhuoqin Yang, Jinzhi Lei

Induced pluripotent stem cells (iPSCs) provide a great model to study the process of reprogramming and differentiation of stem cells. Single-cell RNA sequencing (scRNA-seq) enables…

q-bio.GN2020★ 1 cited

DNA methylation heterogeneity induced by collaborations between enhancers

Yusong Ye, Zhuoqin Yang, Jinzhi Lei

During mammalian embryo development, reprogramming of DNA methylation plays important roles in the erasure of parental epigenetic memory and the establishment of naïve pluripogent…

q-bio.QM2020★ 10 cited

Single-cell entropy to quantify the cellular transcription from single-cell RNA-seq data

Jingxin Liu, You Song, Jinzhi Lei

We present the use of single-cell entropy (scEntropy) to measure the order of the cellular transcriptome profile from single-cell RNA-seq data, which leads to a method of unsupervi…