3 papers
q-bio.QM2026
Rank-and-Reason: Multi-Agent Collaboration Accelerates Zero-Shot Protein Mutation Prediction
Yang Tan, Yuanxi Yu, Can Wu +7
Zero-shot mutation prediction is vital for low-resource protein engineering, yet existing protein language models (PLMs) often yield statistically confident results that ignore fun…
q-bio.QM2025
Sequence-Only Prediction of Binding Affinity Changes: A Robust and Interpretable Model for Antibody Engineering
Chen Liu, Mingchen Li, Yang Tan +3
A pivotal area of research in antibody engineering is to find effective modifications that enhance antibody-antigen binding affinity. Traditional wet-lab experiments assess mutants…
cs.CL2025
VenusFactory: A Unified Platform for Protein Engineering Data Retrieval and Language Model Fine-Tuning
Yang Tan, Chen Liu, Jingyuan Gao +8
Natural language processing (NLP) has significantly influenced scientific domains beyond human language, including protein engineering, where pre-trained protein language models (P…