activity
20232026
most citedExactly solvable statistical physics models for large neuronal populations

3 citations · 4 across the 11 of their papers we have counts for

collaborators

11 papers

physics.bio-ph2026

Emergence of criticality in models of real neurons

David P. Carcamo, Christopher W. Lynn

Critical systems sit near boundaries between qualitatively distinct behaviors. When inferring models of neural activity, this proximity to criticality is thought to require the pre…

physics.bio-ph2025

Quantifying the compressibility of the human brain

Nicholas J. Weaver, Joshua I. Faskowitz, Richard F. Betzel +1

In the human brain, the allowed patterns of activity are constrained by the correlations between brain regions. Yet it remains unclear which correlations -- and how many -- are nee…

physics.bio-ph2025

Neural subspaces, minimax entropy, and mean-field theory for networks of neurons

Luca Di Carlo, Francesca Mignacco, Christopher W. Lynn +1

Recent advances in experimental techniques enable the simultaneous recording of activity from thousands of neurons in the brain, presenting both an opportunity and a challenge: to…

cond-mat.stat-mech2025

Coarse-graining dynamics to maximize irreversibility

Qiwei Yu, Matthew P. Leighton, Christopher W. Lynn

In many far-from-equilibrium biological systems, energy injected by irreversible processes at microscopic scales propagates to larger scales to fulfill important biological functio…

q-bio.QM2025

Minimax entropy: The statistical physics of optimal models

David P. Carcamo, Nicholas J. Weaver, Purushottam D. Dixit +1

When constructing models of the world, we aim for optimal compressions: models that include as few details as possible while remaining as accurate as possible. But which details --…

physics.bio-ph2025

Extended mean-field theories for networks of real neurons

Luca Di Carlo, Francesca Mignacco, Christopher W. Lynn +1

If the behavior of a system with many degrees of freedom can be captured by a small number of collective variables, then plausibly there is an underlying mean-field theory. We show…

physics.bio-ph2025

Direct dependencies between neurons explain activity

Christopher W. Lynn

Our understanding of neural computation is founded on the assumption that neurons fire in response to a linear summation of inputs. Yet experiments demonstrate that some neurons ar…

physics.bio-ph2024

Statistical physics of large-scale neural activity with loops

David P. Carcamo, Christopher W. Lynn

As experiments advance to record from tens of thousands of neurons, statistical physics provides a framework for understanding how collective activity emerges from networks of fine…

physics.bio-ph2024

Exact minimax entropy models of large-scale neuronal activity

Christopher W. Lynn, Qiwei Yu, Rich Pang +2

In the brain, fine-scale correlations combine to produce macroscopic patterns of activity. However, as experiments record from larger and larger populations, we approach a fundamen…

physics.bio-ph2023★ 3 cited

Exactly solvable statistical physics models for large neuronal populations

Christopher W. Lynn, Qiwei Yu, Rich Pang +2

Maximum entropy methods provide a principled path connecting measurements of neural activity directly to statistical physics models, and this approach has been successful for popul…

q-bio.NC2023★ 1 cited

Spontaneous brain activity emerges from pairwise interactions in the larval zebrafish brain

Richard E. Rosch, Dominic R. W. Burrows, Christopher W. Lynn +1

Brain activity is characterized by brain-wide spatiotemporal patterns which emerge from synapse-mediated interactions between individual neurons. Calcium imaging provides access to…