13 citations · 17 across the 7 of their papers we have counts for
5 papers · 1 filter
Saturation effects on T-cell activation in a model of a multi-stage pathogen
Michael Shapiro, Edgar Delgado-Eckert
In previous work, we studied host response to a pathogen which uses a cycle of immunologically distinct stages to establish and maintain infection. We showed that for generic param…
Competition-colonization trade-off promotes coexistence of low-virulence viral strains
Samuel Ojosnegros, Edgar Delgado-Eckert, Niko Beerenwinkel
RNA viruses exist as genetically diverse populations displaying different phenotypes, including diverse degrees of virulence. The evolution of virulence in viral populations is, ho…
A model of host response to a multi-stage pathogen
Edgar Delgado-Eckert, Michael Shapiro
We model the immune surveillance of a pathogen which passes through immunologically distinct stages. The biological parameters of this system induce a partial order on the stag…
The evolution of virulence in RNA viruses under a competition-colonization trade-off
Edgar Delgado-Eckert, Samuel Ojosnegros, Niko Beerenwinkel
RNA viruses exist in large intra-host populations which display great genotypic and phenotypic diversity. We analyze a model of viral competition between two different viral strain…
Finding an individual's probability of infection in an SIR network is NP-hard
Michael Shapiro, Edgar Delgado-Eckert
The celebrated Kermack-McKendric model of epidemics studies the transmission of a disease in a population where each individual is initially susceptible (S), may become infective (…