activity
20072012
most citedThe evolution of virulence in RNA viruses under a competition-colonization trade-off

13 citations · 17 across the 7 of their papers we have counts for

collaborators

8 papers

q-bio.PE2012

Saturation effects on T-cell activation in a model of a multi-stage pathogen

Michael Shapiro, Edgar Delgado-Eckert

In previous work, we studied host response to a pathogen which uses a cycle of immunologically distinct stages to establish and maintain infection. We showed that for generic param…

q-bio.PE2011

Competition-colonization trade-off promotes coexistence of low-virulence viral strains

Samuel Ojosnegros, Edgar Delgado-Eckert, Niko Beerenwinkel

RNA viruses exist as genetically diverse populations displaying different phenotypes, including diverse degrees of virulence. The evolution of virulence in viral populations is, ho…

q-bio.PE2010

A model of host response to a multi-stage pathogen

Edgar Delgado-Eckert, Michael Shapiro

We model the immune surveillance of a pathogen which passes through immunologically distinct stages. The biological parameters of this system induce a partial order on the stag…

q-bio.PE2010★ 13 cited

The evolution of virulence in RNA viruses under a competition-colonization trade-off

Edgar Delgado-Eckert, Samuel Ojosnegros, Niko Beerenwinkel

RNA viruses exist in large intra-host populations which display great genotypic and phenotypic diversity. We analyze a model of viral competition between two different viral strain…

q-bio.PE2010★ 1 cited

Finding an individual's probability of infection in an SIR network is NP-hard

Michael Shapiro, Edgar Delgado-Eckert

The celebrated Kermack-McKendric model of epidemics studies the transmission of a disease in a population where each individual is initially susceptible (S), may become infective (…

math.DS2007★ 2 cited

An algebraic and graph theoretical framework to study monomial dynamical systems over a finite field

Edgar Delgado-Eckert

An n dimensional monomial dynamical system over a finite field K is a nonlinear deterministic time discrete dynamical system with the property that each of the n component function…

q-bio.QM2007

Reverse engineering time discrete finite dynamical systems: A feasible undertaking?

Edgar Delgado-Eckert

With the advent of high-throughput profiling methods, interest in reverse engineering the structure and dynamics of biochemical networks is high. Recently an algorithm for reverse…

math.AC2007★ 1 cited

Canonical representatives for residue classes of a polynomial ideal and orthogonality

Edgar Delgado-Eckert

The aim of this paper is to unveil an unexpected relationship between the normal form of a polynomial with respect to a polynomial ideal and the more geometric concept of orthogona…