178 citations · 602 across the 8 of their papers we have counts for
3 papers · 1 filter
Jamming proteins with slipknots and their free energy landscape
Joanna I. Sułkowska, Piotr Sułkowski, José N. Onuchic
Theoretical studies of stretching proteins with slipknots reveal a surprising growth of their unfolding times when the stretching force crosses an intermediate threshold. This beha…
Dodging the crisis of folding proteins with knots
Joanna I. Sułkowska, Piotr Sułkowski, José N. Onuchic
Proteins with nontrivial topology, containing knots and slipknots, have the ability to fold to their native states without any additional external forces invoked. A mechanism is su…
Mechanical Strength of 17 134 Model Proteins and Cysteine Slipknots
Mateusz Sikora, Joanna I. Sułkowska, Marek Cieplak
A new theoretical survey of proteins' resistance to constant speed stretching is performed for a set of 17 134 proteins as described by a structure-based model. The proteins select…