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q-bio.NC2007
Wide therapeutic time window for nimesulide neuroprotection in a model of transient focal cerebral ischemia in the rat
E. Candelario-Jalil, A. Gonzalez-Falcon, M. Garcia-Cabrera +2
Results from several studies indicate that cyclooxygenase-2 (COX-2) is involved in ischemic brain injury. The purpose of this study was to evaluate the neuroprotective effects of t…
q-bio.NC2007
Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte infiltration following transient focal cerebral ischaemia in rats
E Candelario-Jalil, A Gonzalez-Falcon, M Garcia-Cabrera +2
Several studies suggest that cyclooxygenase (COX)-2 plays a pivotal role in the progression of ischaemic brain damage. In the present study, we investigated the effects of selectiv…