312 citations · 1.9k across the 52 of their papers we have counts for
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Formal properties of the probability of fixation: identities, inequalities and approximations
David M. McCandlish, Charles L. Epstein, Joshua B. Plotkin
The formula for the probability of fixation of a new mutation is widely used in theoretical population genetics and molecular evolution. Here we derive a series of identities, ineq…
The inevitability of unconditionally deleterious substitutions during adaptation
David M. McCandlish, Charles L. Epstein, Joshua B. Plotkin
Studies on the genetics of adaptation typically neglect the possibility that a deleterious mutation might fix. Nonetheless, here we show that, in many regimes, the first substituti…
The equilibrium allele frequency distribution for a population with reproductive skew
Ricky Der, Joshua B. Plotkin
We study the population genetics of two neutral alleles under reversible mutation in the Λ-processes, a population model that features a skewed offspring distribution. We describe…
From extortion to generosity, the evolution of zero-determinant strategies in the prisoner's dilemma
Alexander J. Stewart, Joshua B. Plotkin
Recent work has revealed a new class of "zero-determinant" (ZD) strategies for iterated, two-player games. ZD strategies allow a player to unilaterally enforce a linear relationshi…
Identifying Signatures of Selection in Genetic Time Series
Alison Feder, Sergey Kryazhimskiy, Joshua B. Plotkin
Both genetic drift and natural selection cause the frequencies of alleles in a population to vary over time. Discriminating between these two evolutionary forces, based on a time s…