312 citations · 1.9k across the 52 of their papers we have counts for
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q-bio.PE2012★ 1 cited
Selection biases the prevalence and type of epistasis along adaptive trajectories
Jeremy A. Draghi, Joshua B. Plotkin
The contribution to an organism's phenotype from one genetic locus may depend upon the status of other loci. Such epistatic interactions among loci are now recognized as fundamenta…
q-bio.PE2012★ 15 cited
The evolution of complex gene regulation by low specificity binding sites
Alexander J. Stewart, Joshua B. Plotkin
Transcription factor binding sites vary in their specificity, both within and between species. Binding specificity has a strong impact on the evolution of gene expression, because…
q-bio.PE2012★ 24 cited
The evolution of genetic architectures underlying quantitative traits
Etienne Rajon, Joshua B. Plotkin
In the classic view introduced by R. A. Fisher, a quantitative trait is encoded by many loci with small, additive effects. Recent advances in QTL mapping have begun to elucidate th…