4 citations · 12 across the 32 of their papers we have counts for
33 papers
MORI-Seg: Learning Morphological Geometry for Instance Segmentation without Instance Annotations
Leiyue Zhao, Tianyu Shi, Daniel Reisenbuchler +12
Instance-level quantification of kidney functional units is essential for morphometric analysis, yet most publicly available pathology datasets provide only semantic segmentation a…
DUET: Dual-Paradigm Adaptive Expert Triage with Single-cell Inductive Prior for Spatial Transcriptomics Prediction
Junchao Zhu, Ruining Deng, Junlin Guo +11
Inferring spatially resolved gene expression from histology images offers a cost-effective complement to spatial transcriptomics (ST). However, existing methods reduce this task to…
How Close Are We? Limitations and Progress of AI Models in Banff Lesion Scoring
Yanfan Zhu, Juming Xiong, Ruining Deng +7
The Banff Classification provides the global standard for evaluating renal transplant biopsies, yet its semi-quantitative nature, complex criteria, and inter-observer variability p…
Evaluating New AI Cell Foundation Models on Challenging Kidney Pathology Cases Unaddressed by Previous Foundation Models
Runchen Wang, Junlin Guo, Siqi Lu +12
Accurate cell nuclei segmentation is critical for downstream tasks in kidney pathology and remains a major challenge due to the morphological diversity and imaging variability of r…
MedFoundationHub: A Lightweight and Secure Toolkit for Deploying Medical Vision Language Foundation Models
Xiao Li, Yanfan Zhu, Ruining Deng +6
Recent advances in medical vision-language models (VLMs) open up remarkable opportunities for clinical applications such as automated report generation, copilots for physicians, an…
Fine-grained Multi-class Nuclei Segmentation with Molecular-empowered All-in-SAM Model
Xueyuan Li, Can Cui, Ruining Deng +7
Purpose: Recent developments in computational pathology have been driven by advances in Vision Foundation Models, particularly the Segment Anything Model (SAM). This model facilita…
DyMorph-B2I: Dynamic and Morphology-Guided Binary-to-Instance Segmentation for Renal Pathology
Leiyue Zhao, Yuechen Yang, Yanfan Zhu +7
Accurate morphological quantification of renal pathology functional units relies on instance-level segmentation, yet most existing datasets and automated methods provide only binar…
Img2ST-Net: Efficient High-Resolution Spatial Omics Prediction from Whole Slide Histology Images via Fully Convolutional Image-to-Image Learning
Junchao Zhu, Ruining Deng, Junlin Guo +10
Recent advances in multi-modal AI have demonstrated promising potential for generating the currently expensive spatial transcriptomics (ST) data directly from routine histology ima…
ZeroReg3D: A Zero-shot Registration Pipeline for 3D Consecutive Histopathology Image Reconstruction
Juming Xiong, Ruining Deng, Jialin Yue +10
Histological analysis plays a crucial role in understanding tissue structure and pathology. While recent advancements in registration methods have improved 2D histological analysis…
Quantitative Benchmarking of Anomaly Detection Methods in Digital Pathology
Can Cui, Xindong Zheng, Ruining Deng +8
Anomaly detection has been widely studied in the context of industrial defect inspection, with numerous methods developed to tackle a range of challenges. In digital pathology, ano…
IRS: Incremental Relationship-guided Segmentation for Digital Pathology
Ruining Deng, Junchao Zhu, Juming Xiong +14
Continual learning is rapidly emerging as a key focus in computer vision, aiming to develop AI systems capable of continuous improvement, thereby enhancing their value and practica…
CASC-AI: Consensus-aware Self-corrective Learning for Noise Cell Segmentation
Ruining Deng, Yihe Yang, David J. Pisapia +15
Multi-class cell segmentation in high-resolution gigapixel whole slide images (WSIs) is crucial for various clinical applications. However, training such models typically requires…
MagNet: Multi-Level Attention Graph Network for Predicting High-Resolution Spatial Transcriptomics
Junchao Zhu, Ruining Deng, Tianyuan Yao +12
The rapid development of spatial transcriptomics (ST) offers new opportunities to explore the gene expression patterns within the spatial microenvironment. Current research integra…
KPIs 2024 Challenge: Advancing Glomerular Segmentation from Patch- to Slide-Level
Ruining Deng, Tianyuan Yao, Yucheng Tang +44
Chronic kidney disease (CKD) is a major global health issue, affecting over 10% of the population and causing significant mortality. While kidney biopsy remains the gold standard f…
Towards Fine-grained Renal Vasculature Segmentation: Full-Scale Hierarchical Learning with FH-Seg
Yitian Long, Zhongze Wu, Xiu Su +4
Accurate fine-grained segmentation of the renal vasculature is critical for nephrological analysis, yet it faces challenges due to diverse and insufficiently annotated images. Exis…
PySpatial: A High-Speed Whole Slide Image Pathomics Toolkit
Yuechen Yang, Yu Wang, Tianyuan Yao +5
Whole Slide Image (WSI) analysis plays a crucial role in modern digital pathology, enabling large-scale feature extraction from tissue samples. However, traditional feature extract…
ASIGN: An Anatomy-aware Spatial Imputation Graphic Network for 3D Spatial Transcriptomics
Junchao Zhu, Ruining Deng, Tianyuan Yao +9
Spatial transcriptomics (ST) is an emerging technology that enables medical computer vision scientists to automatically interpret the molecular profiles underlying morphological fe…
Glo-In-One-v2: Holistic Identification of Glomerular Cells, Tissues, and Lesions in Human and Mouse Histopathology
Lining Yu, Mengmeng Yin, Ruining Deng +9
Segmenting glomerular intraglomerular tissue and lesions traditionally depends on detailed morphological evaluations by expert nephropathologists, a labor-intensive process suscept…
GloFinder: AI-empowered QuPath Plugin for WSI-level Glomerular Detection, Visualization, and Curation
Jialin Yue, Tianyuan Yao, Ruining Deng +7
Artificial intelligence (AI) has demonstrated significant success in automating the detection of glomeruli, the key functional units of the kidney, from whole slide images (WSIs) i…
Evaluating Cell AI Foundation Models in Kidney Pathology with Human-in-the-Loop Enrichment
Junlin Guo, Siqi Lu, Can Cui +14
Training AI foundation models has emerged as a promising large-scale learning approach for addressing real-world healthcare challenges, including digital pathology. While many of t…
Cross-Species Data Integration for Enhanced Layer Segmentation in Kidney Pathology
Junchao Zhu, Mengmeng Yin, Ruining Deng +6
Accurate delineation of the boundaries between the renal cortex and medulla is crucial for subsequent functional structural analysis and disease diagnosis. Training high-quality de…
Assessment of Cell Nuclei AI Foundation Models in Kidney Pathology
Junlin Guo, Siqi Lu, Can Cui +14
Cell nuclei instance segmentation is a crucial task in digital kidney pathology. Traditional automatic segmentation methods often lack generalizability when applied to unseen datas…
PFPs: Prompt-guided Flexible Pathological Segmentation for Diverse Potential Outcomes Using Large Vision and Language Models
Can Cui, Ruining Deng, Junlin Guo +4
The Vision Foundation Model has recently gained attention in medical image analysis. Its zero-shot learning capabilities accelerate AI deployment and enhance the generalizability o…
HoloHisto: End-to-end Gigapixel WSI Segmentation with 4K Resolution Sequential Tokenization
Yucheng Tang, Yufan He, Vishwesh Nath +11
In digital pathology, the traditional method for deep learning-based image segmentation typically involves a two-stage process: initially segmenting high-resolution whole slide ima…