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stat.ME2025
Power and sample size calculation for multivariate longitudinal trials using the longitudinal rank sum test
Dhrubajyoti Ghosh, Xiaoming Xu, Sheng Luo
Neurodegenerative diseases such as Alzheimer's and Parkinson's often exhibit complex, multivariate longitudinal outcomes that require advanced statistical methods to comprehensivel…
stat.ME2024★ 3 cited
A novel longitudinal rank-sum test for multiple primary endpoints in clinical trials: Applications to neurodegenerative disorders
Xiaoming Xu, Dhrubajyoti Ghosh, Sheng Luo
Neurodegenerative disorders such as Alzheimer's disease (AD) present a significant global health challenge, characterized by cognitive decline, functional impairment, and other deb…
stat.ME2024
A non-parametric U-statistic testing approach for multi-arm clinical trials with multivariate longitudinal data
Dhrubajyoti Ghosh, Sheng Luo
Randomized clinical trials (RCTs) often involve multiple longitudinal primary outcomes to comprehensively assess treatment efficacy. The Longitudinal Rank-Sum Test (LRST), a robust…