17 citations · 32 across the 7 of their papers we have counts for
4 papers · 1 filter
Integrated Population Balance and Multiphysics Modeling for Predicting Undesired Agglomeration in Small Molecule Manufacturing
Prakitr Srisuma, Peter Hou, Shashank Venkat Muddu +3
Agitated filter dryers (AFDs) are a crucial unit operation in small molecule manufacturing that enables simultaneous filtration, washing, and drying of active pharmaceutical ingred…
Probabilistically Robust Uncertainty Analysis and Optimal Control of Continuous Lyophilization via Polynomial Chaos Theory
Prakitr Srisuma, George Barbastathis, Richard D. Braatz
Lyophilization, aka freeze drying, is a process commonly used to increase the stability of various drug products in biotherapeutics manufacturing, e.g., mRNA vaccines, allowing for…
Mechanistic Modeling of Continuous Lyophilization for Biopharmaceutical Manufacturing
Prakitr Srisuma, Gang Chen, Richard D. Braatz
Lyophilization (aka freeze drying) is a typical process in pharmaceutical manufacturing used for improving the stability of various drug products, including its recent applications…
Mechanistic Modeling and Analysis of Thermal Radiation in Conventional, Microwave-assisted, and Hybrid Freeze Drying for Biopharmaceutical Manufacturing
Prakitr Srisuma, George Barbastathis, Richard D. Braatz
In freeze drying, thermal radiation has a significant effect on the drying process of vials located near the corner and edge of the trays, resulting in non-uniformity of the produc…