79 citations · 109 across the 3 of their papers we have counts for
3 papers
Affinity and valence impact the extent and symmetry of phase separation of multivalent proteins
Saroj Kumar Nandi, Daniel Österle, Meta Heidenreich +2
Biomolecular self-assembly spatially segregates proteins with a limited number of binding sites (valence) into condensates that coexist with a dilute phase. We develop a many-body…
The self-assembly and evolution of homomeric protein complexes
Gabriel Villar, Alex W. Wilber, Alex J. Williamson +6
We introduce a simple "patchy particle" model to study the thermodynamics and dynamics of self-assembly of homomeric protein complexes. Our calculations allow us to rationalize rec…
Probabilistic annotation of protein sequences based on functional classifications
Emmanuel D. Levy, Christos A. Ouzounis, Walter R. Gilks +1
BACKGROUND: One of the most evident achievements of bioinformatics is the development of methods that transfer biological knowledge from characterised proteins to uncharacterised s…