10 citations · 22 across the 16 of their papers we have counts for
16 papers
Open-MOPD: Diagnosing and Fixing Capability Imbalance in Multi-Teacher On-Policy Distillation
Huan-ang Gao, Haohan Chi, Yong Yan +7
Multi-teacher on-policy distillation (M-OPD) has emerged as a promising paradigm for consolidating domain-specialized reinforcement learning (RL) experts into a single generalist s…
Beyond Euclidean Clipping: Overcoming Exploration Collapse in LLM RL via Riemannian Isometric Policy Optimization
Zhicheng Cai, Xinyuan Guo, Hanlin Wu +4
Reinforcement learning (RL) has become a dominant paradigm for enhancing LLMs' reasoning capabilities. However, RL algorithms with PPO-Clip are inherently limited by exploration co…
Weak-to-Strong Generalization via Direct On-Policy Distillation
Shiyuan Feng, Huan-ang Gao, Haohan Chi +7
Reinforcement learning with verifiable rewards (RLVR) is a powerful recipe for improving language-model reasoning, but it is expensive to repeat on every new strong model because t…
Spectral Rewiring for Exploration, Purification, and Model Merging
Zhilong Zhang, Hongli Yu, Huan-ang Gao +5
Reinforcement learning has become a standard post-training recipe for large language models, but dense full-parameter updates create two deployment-relevant bottlenecks: suppressed…
DCFold: Efficient Protein Structure Generation with Single Forward Pass
Zhe Zhang, Yuanning Feng, Yuxuan Song +3
AlphaFold3 introduces a diffusion-based architecture that elevates protein structure prediction to all-atom resolution with improved accuracy. This state-of-the-art performance has…
ShortListing Model: A Streamlined SimplexDiffusion for Discrete Variable Generation
Yuxuan Song, Zhe Zhang, Yu Pei +7
Generative modeling of discrete variables is challenging yet crucial for applications in natural language processing and biological sequence design. We introduce the Shortlisting M…
MemAgent: Reshaping Long-Context LLM with Multi-Conv RL-based Memory Agent
Hongli Yu, Tinghong Chen, Jiangtao Feng +8
Despite improvements by length extrapolation, efficient attention and memory modules, handling infinitely long documents with linear complexity without performance degradation duri…
Piloting Structure-Based Drug Design via Modality-Specific Optimal Schedule
Keyue Qiu, Yuxuan Song, Zhehuan Fan +5
Structure-Based Drug Design (SBDD) is crucial for identifying bioactive molecules. Recent deep generative models are faced with challenges in geometric structure modeling. A major…
Steering Protein Family Design through Profile Bayesian Flow
Jingjing Gong, Yu Pei, Siyu Long +7
Protein family design emerges as a promising alternative by combining the advantages of de novo protein design and mutation-based directed evolution.In this paper, we propose Profi…
A Periodic Bayesian Flow for Material Generation
Hanlin Wu, Yuxuan Song, Jingjing Gong +6
Generative modeling of crystal data distribution is an important yet challenging task due to the unique periodic physical symmetry of crystals. Diffusion-based methods have shown e…
ACDiT: Interpolating Autoregressive Conditional Modeling and Diffusion Transformer
Jinyi Hu, Shengding Hu, Yuxuan Song +6
Autoregressive and diffusion models have achieved remarkable progress in language models and visual generation, respectively. We present ACDiT, a novel Autoregressive blockwise Con…
Empower Structure-Based Molecule Optimization with Gradient Guided Bayesian Flow Networks
Keyue Qiu, Yuxuan Song, Jie Yu +7
Structure-Based molecule optimization (SBMO) aims to optimize molecules with both continuous coordinates and discrete types against protein targets. A promising direction is to exe…
MolCRAFT: Structure-Based Drug Design in Continuous Parameter Space
Yanru Qu, Keyue Qiu, Yuxuan Song +5
Generative models for structure-based drug design (SBDD) have shown promising results in recent years. Existing works mainly focus on how to generate molecules with higher binding…
Unified Generative Modeling of 3D Molecules via Bayesian Flow Networks
Yuxuan Song, Jingjing Gong, Yanru Qu +4
Advanced generative model (e.g., diffusion model) derived from simplified continuity assumptions of data distribution, though showing promising progress, has been difficult to appl…
Equivariant Flow Matching with Hybrid Probability Transport
Yuxuan Song, Jingjing Gong, Minkai Xu +5
The generation of 3D molecules requires simultaneously deciding the categorical features~(atom types) and continuous features~(atom coordinates). Deep generative models, especially…
RetroDiff: Retrosynthesis as Multi-stage Distribution Interpolation
Yiming Wang, Yuxuan Song, Yiqun Wang +4
Retrosynthesis poses a key challenge in biopharmaceuticals, aiding chemists in finding appropriate reactant molecules for given product molecules. With reactants and products repre…