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20242026
most citedGeneralist versus Specialist Vision Foundation Models for Ocular Disease and Oculomics

2 citations · 6 across the 17 of their papers we have counts for

collaborators

18 papers

q-bio.QM2026

Prediction bias in biological ageing markers

Yiqun Lin, Ariel Yuhan Ong, Matthew Yu Heng Wong +52

Biological ageing markers have attracted growing interest, with models estimating age from organ imaging or blood biomarkers. An estimated age above chronological age or the age-sp…

cs.CV2026

Beyond Natural-Image Foundation Models: Benchmarking Satellite Pretraining for Ophthalmic Image Analysis

Lovre Antonio Budimir, Mingya Alexa Gong, Alyssa Foong Quinney +5

Vision Foundation Models (VFMs) have emerged as a promising approach in medical imaging, producing broadly applicable systems that can be efficiently adapted across diverse imaging…

cs.CV2026

Representation Transfer of Foundation Models for Ultra-Widefield Retinal Imaging

Mingya Alexa Gong, Da Ma, Lovre Antonio Budimir +7

Despite the widespread adoption of foundation models as feature extractors for medical imaging, relatively little is understood about how different pretraining strategies influence…

cs.CV2026

PC-Seg: Progressive Cross-View Consistency for 3D OCT Segmentation from Sparse 2D Annotations

Tsubasa Konno, Takahiro Ninomiya, Yukun Zhou +6

Volumetric segmentation of optical coherence tomography (OCT) images is essential for diagnosing ocular diseases but requires labor-intensive voxel-wise annotations. While semi-sup…

cs.HC2026

Vibe coding for clinicians: democratising bespoke software development for digital health innovation

Ariel Yuhan Ong, Iain Livingstone, Caroline Kilduff +5

Clinicians often face workflow problems that are perceived as either too bespoke or low stakes to attract commercial attention. Historically, most do not have the technical knowled…

cs.CY2026

Deliberative multi-agent large language models improve clinical reasoning in ophthalmology

Ehsan Misaghi, Sean T Berkowitz, Bing Yu Chen +10

Large language models (LLMs) show potential for ophthalmic clinical reasoning, yet individual models risk introducing harm. We evaluated whether multi-agent LLM deliberative counci…

cs.LG2026

oculomix: Hierarchical Sampling for Retinal-Based Systemic Disease Prediction

Hyunmin Kim, Yukun Zhou, Rahul A. Jonas +4

Oculomics - the concept of predicting systemic diseases, such as cardiovascular disease and dementia, through retinal imaging - has advanced rapidly due to the data efficiency of t…

cs.CV2025

Native Intelligence Emerges from Large-Scale Clinical Practice: A Retinal Foundation Model with Deployment Efficiency

Jia Guo, Jiawei Du, Shengzhu Yang +21

Current retinal foundation models remain constrained by curated research datasets that lack authentic clinical context, and require extensive task-specific optimization for each ap…

cs.HC2025

Complementary Human-AI Clinical Reasoning in Ophthalmology

Mertcan Sevgi, Fares Antaki, Abdullah Zafar Khan +26

Vision impairment and blindness are a major global health challenge where gaps in the ophthalmology workforce limit access to specialist care. We evaluate AMIE, a medically fine-tu…

eess.IV2025★ 2 cited

Generalist versus Specialist Vision Foundation Models for Ocular Disease and Oculomics

Yukun Zhou, Paul Nderitu, Jocelyn Hui Lin Goh +20

Medical foundation models, pre-trained with large-scale clinical data, demonstrate strong performance in diverse clinically relevant applications. RETFound, trained on nearly one m…

cs.CV2025

FusionFM: Fusing Eye-specific Foundational Models for Optimized Ophthalmic Diagnosis

Ke Zou, Jocelyn Hui Lin Goh, Yukun Zhou +11

Foundation models (FMs) have shown great promise in medical image analysis by improving generalization across diverse downstream tasks. In ophthalmology, several FMs have recently…

cs.CL2025★ 1 cited

Performance of GPT-5 Frontier Models in Ophthalmology Question Answering

Fares Antaki, David Mikhail, Daniel Milad +11

Large language models (LLMs) such as GPT-5 integrate advanced reasoning capabilities that may improve performance on complex medical question-answering tasks. For this latest gener…

cs.CV2025★ 1 cited

Delving into Out-of-Distribution Detection with Medical Vision-Language Models

Lie Ju, Sijin Zhou, Yukun Zhou +4

Recent advances in medical vision-language models (VLMs) demonstrate impressive performance in image classification tasks, driven by their strong zero-shot generalization capabilit…

eess.IV2025

Is an Ultra Large Natural Image-Based Foundation Model Superior to a Retina-Specific Model for Detecting Ocular and Systemic Diseases?

Qingshan Hou, Yukun Zhou, Jocelyn Hui Lin Goh +19

The advent of foundation models (FMs) is transforming medical domain. In ophthalmology, RETFound, a retina-specific FM pre-trained sequentially on 1.4 million natural images and 1.…

cs.CV2025

Are Traditional Deep Learning Model Approaches as Effective as a Retinal-Specific Foundation Model for Ocular and Systemic Disease Detection?

Samantha Min Er Yew, Xiaofeng Lei, Jocelyn Hui Lin Goh +26

Background: RETFound, a self-supervised, retina-specific foundation model (FM), showed potential in downstream applications. However, its comparative performance with traditional d…

cs.CV2025★ 1 cited

Enhancing Contrastive Learning for Retinal Imaging via Adjusted Augmentation Scales

Zijie Cheng, Boxuan Li, André Altmann +2

Contrastive learning, a prominent approach within self-supervised learning, has demonstrated significant effectiveness in developing generalizable models for various applications i…

cs.CV2024

Block Expanded DINORET: Adapting Natural Domain Foundation Models for Retinal Imaging Without Catastrophic Forgetting

Jay Zoellin, Colin Merk, Mischa Buob +12

Integrating deep learning into medical imaging is poised to greatly advance diagnostic methods but it faces challenges with generalizability. Foundation models, based on self-super…

eess.IV2024★ 1 cited

Enhancing Diagnostic Accuracy in Rare and Common Fundus Diseases with a Knowledge-Rich Vision-Language Model

Meng Wang, Tian Lin, Aidi Lin +46

Previous foundation models for fundus images were pre-trained with limited disease categories and knowledge base. Here we introduce a knowledge-rich vision-language model (RetiZero…